Stephen Tsang, M.D., Ph.D. explores new pathways into disease etiology and therapeutics with patient-specific stem cells

Recently, scientific researchers have begun exploring new pathways into disease etiology, drug development, and cell therapeutics by using induced pluripotent stem cells (iPS cells) created from patient cells.  In his research laboratory, Stephen Tsang, M.D., Ph.D., generated iPS cells from two patients with retinitis pigmentosa, a form of inherited blindness caused by a gene mutation.  By taking these iPS cells and delivering a copy of them via gene-therapy, Dr. Tsang was able to reverse the defects that this particular gene mutation causes, helping to advance the development of genomic science. Read more about Dr. Tsang’s work in precision medicine and patient-specific therapy featured in the current issue of SCIENCE.