- Most commonly associated with contact lens use, corneal trauma and history of exposure to possibly contaminated fresh water.
- Foreign body sensation, severe ocular pain, photophobia and blurred vision
- Often pain is more severe than signs in early course of the disease
- Usually unilateral diffuse punctate epitheliopathy, dendritic epithelial lesion which may gradually progress to stromal infection associated with ring infiltrate formation
- Enlarged corneal nerve ( keratoneuritis) is patognomonic of the infection
- Scleritis may be found in advanced cases
- Early diagnosis a prognostic factor of a successful outcome.
- Epithelial debridement.
- Topical anti-amoeba agents.
- Penetrating keratoplasty in a severe progressive keratitis.