Most commonly associated with contact lens use, corneal trauma and history of exposure to possibly contaminated fresh water.
Clinical Features
Symptoms:
Foreign body sensation, severe ocular pain, photophobia and blurred vision
Often pain is more severe than signs in early course of the disease
Signs:
Usually unilateral diffuse punctate epitheliopathy, dendritic epithelial lesion which may gradually progress to stromal infection associated with ring infiltrate formation
Enlarged corneal nerve ( keratoneuritis) is patognomonic of the infection
Scleritis may be found in advanced cases
Management
Early diagnosis a prognostic factor of a successful outcome.
Epithelial debridement.
Topical anti-amoeba agents.
Penetrating keratoplasty in a severe progressive keratitis.