More commonly seen in older, fair-skinned individuals
Usually occurs as a localized, slightly elevated, minimally invasive, and remains confined to the epithelium
May infrequently invade the underlying stroma and metastasize to regional lymph nodes
Recurrences are common
Clinical features:
Nodular, or irregular white lesions (leukoplakia) that may occur anywhere in the conjunctiva or cornea, most commonly at the limbus in interpalpebral fissure
Fleshy or frothy vascularized lesions that simulate benign conjunctival squamous papilloma
Diffuse, translucent gray area of conjuctival intraepithelial neoplasia involving the cornea
Management:
Surgical excision with cryotherapy and/or alcohol application
Use of topical chemotherapy with mitomycin C, 5-fluorouracil, or interferon
