Morning Glory Anomaly

Morning Glory Anomaly of the Optic Nerve 

  • Rare case and usually unilateral.
  • Affects women more than men with a ratio of 2:1.

Clinical features:

  • Symptoms: poor vision, amblyopia and strabismus.
  • Signs:
    • Leukokoria in the first months or years of life
    • Funnel-shaped, excavation of the optic disc and peripapillary retina
    • Enlarged disc with indistinct border surrounded by depigmented areas
    • White, elevated, hyperplastic glial tissues occupies the central disc
    • Abnormally narrow, straight vessels radiated from the disc margins
  • Increased risk of non-rhegmatogenous serous retinal detachment.
  • May be associated with basal encephalocele in patients with mid-line facial defect.