Vitreous Amyloidosis

Vitreous Amyloidosis 

  • Maybe an isolated finding or as a part of systemic amyloidosis.
  • Can be hereditary such as in Familial Amyloidotic Polyneuropathy or nonhereditary.

Clinical features:

  • Symptoms: slowly progressive bilateral or unilateral decreased in visual acuity.
  • Signs:
    • Unilateral or bilateral typical "glass-wool" or "cobweb" appearance of vitreous opacities
    • Hazy view of the fundus
  • Management: therapeutic vitrectomy in visually significant cases.