- Instructor in Neurology (in Ophthalmology)
Linus D. Sun, MD, PhD, manages both basic science and translational research laboratories. Utilizing a monkey model, his lab’s basic science mission is to decode the brain’s eye position signal and how it manifests in human disease. Dr. Sun made the discovery that cortical ocular proprioception is a fundamental brain signal that stabilizes ocular orientation and eye position coding in other parts of the brain. Recently his lab discovered that ocular proprioception is crucial in forming visual spatial memories as well as having a role in the development of intermittent exotropia (strabismus). His clinical mission is to evaluate and treat patients that develop eye movement disorders such as lazy eye, diplopia (double vision), convergence insufficiency, and progressive supranuclear palsy. These syndromes manifest in patients with neurodegenerative disease, stroke, multiple sclerosis, myasthenia gravis, and traumatic brain injury. By quantifying the psychophysics of eye movements, Dr. Sun’s laboratory utilizes oculomotor physiology as a biomarker for assessing outcomes of treatments of novel pharmaceuticals and visuo-motor rehabilitation strategies.
Dr. Sun is a nationally recognized physician-scientist whose active research programs that studies disorders and treatments of the visual nervous system.
Dr. Sun completed his undergraduate training and research with honors in Molecular Biology at UC Berkeley. He received his PhD at Massachusetts Institutes of Technology where he studied the molecular basis and neurophysiology of learning and memory. After his medical training and internship at Yale University School of Medicine he completed a residency in Neurology at Columbia University Medical Center (CUMC) and was the first recipient for his department of a competitive National Institutes of Health (NIH) research fellowship for an investigation in visual neuroscience. Dr. Sun joined the department of Ophthalmology as the principle investigator of a competitive NIH funded research grant investigating the neurological basis on how the brain processes visual information and eye movements, mentored by Dr. Michael E. Goldberg (Professor at CUMC, Society for Neuroscience President Alumnus, and member of the National Academy of Science).
- PhD, Massachusetts Institute of Technology
- MD, Yale University School of Medicine
- Internship: Yale-New Haven Hospital
- Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
Education & Training
RESEARCH TO PREVENT BLINDNESS (Private)
Jan 4 1993 - Dec 31 2018
ROLE OF OCULOMOTOR PROPRIOCEPTION IN SPATIAL PROCESSING BY THE PARIETAL CORTEX (Federal Gov)
Apr 1 2013 - Mar 31 2018
THE NEUROPHYSIOLOGY OF SPATIAL VISION (Federal Gov)
Aug 1 2009 - Jul 31 2015
R25 NEUROLOGY RESEARCH EDUCATION AND MENTORSHIP PROGRAM (Federal Gov)
Mar 15 2010 - Jun 30 2015